|
From the Division of Urology, Faculty of Medicine and Dentistry, University of Western Ontario, London, Ont.
Abstract
DRAMATIC ADVANCES IN THE MANAGEMENT of erectile dysfunction have occurred over the past decade. Oral therapy with vasoactive agents has emerged as first-line treatment and has transformed both the manner in which the public views erectile dysfunction and the way health care providers deliver care. Whereas an extensive investigation was previously common in the management of erectile dysfunction, recent treatment guidelines promote a more minimalist, goal-oriented approach. In this article, we review the physiology of erection, and the pathophysiology, diagnosis and clinical management of erectile dysfunction. We also present the existing evidence for the efficacy of 3 phosphodiesterase inhibitors, the most widely used class of agents for erectile dysfunction.
This article has been cited by other articles:
![]() |
A. Tsertsvadze, H. A. Fink, F. Yazdi, R. MacDonald, A. J. Bella, M. T. Ansari, C. Garritty, K. Soares-Weiser, R. Daniel, M. Sampson, et al. Oral Phosphodiesterase-5 Inhibitors and Hormonal Treatments for Erectile Dysfunction: A Systematic Review and Meta-analysis Ann Intern Med, November 3, 2009; 151(9): 650 - 661. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Tsertsvadze, H. A. Fink, F. Yazdi, R. MacDonald, A. J. Bella, M. T. Ansari, C. Garritty, K. Soares-Weiser, R. Daniel, M. Sampson, et al. Oral Phosphodiesterase-5 Inhibitors and Hormonal Treatments for Erectile Dysfunction: A Systematic Review and Meta-analysis Ann Intern Med, October 19, 2009; (2009) 0000605-200911030-00150v1. [Abstract] [Full Text] |
||||
![]() |
E. Wooltorton Visual loss with erectile dysfunction medications Can. Med. Assoc. J., August 15, 2006; 175(4): 355 - 355. [Full Text] [PDF] |
||||
![]() |
C. E. Teixeira, F. B. M. Priviero, and R. C. Webb Differential Effects of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Vardenafil, and Tadalafil in Rat Aorta J. Pharmacol. Exp. Ther., February 1, 2006; 316(2): 654 - 661. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. M Setter, J. L Iltz, J. E Fincham, R K. Campbell, and D. E Baker Phosphodiesterase 5 Inhibitors for Erectile Dysfunction Ann. Pharmacother., July 1, 2005; 39(7): 1286 - 1295. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. Danby Does testosterone affect effect? Can. Med. Assoc. J., September 14, 2004; 171(6): 553 - 553. [Full Text] [PDF] |
||||
![]() |
G. Brock Does testosterone affect effect? Can. Med. Assoc. J., September 14, 2004; 171(6): 553 - 553. [Full Text] [PDF] |
||||
Read all eLetters